But wasn’t this what it was designed for?

A daily dose of Viagra could become a safe treatment for heart disease, researchers have said, after finding it improved blood flow.

The drug, normally used to treat erectile dysfunction, was found to prevent changes to the heart associated with disease.

Didn’t they originally make it with an eye on heart disease and then switched because everyone taking it had a permanent stiffie?

8 comments on “But wasn’t this what it was designed for?

  1. Have there not been problems associated with too much viagra?
    Never mind that some people react badly with even one dose of it.

  2. This is a famous story. The old men on the study apparently refused to hand their pills back:

    http://en.wikipedia.org/wiki/Sildenafil#Origins

    Sildenafil (compound UK-92,480) was synthesized by a group of pharmaceutical chemists working at Pfizer’s Sandwich, Kent, research facility in England. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease). The first clinical trials were conducted in Morriston Hospital in Swansea.[44] Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections.[2][45] Pfizer therefore decided to market it for erectile dysfunction, rather than for angina.

    The real question is why it is so rare to find this sold over the counter? I mean, what harm would it do?

  3. and here I thought it was developed for use in geriatric facilities to prevent the old men from rolling out of their beds at night.

  4. It binds to the wrong phosphodiesterase (PDE 3) to work as an anti-angina drug, but for relaxing the smooth muscle in the corpus cavernosum and allowing increased blood flow it’s great. It binds mainly to PDE 5 and weakly to PDE 6, both active in colour vision, which is why a commonly observed side effect is perceiving a faint blue tinge or halo, and also sometimes photosensitivity. (Not a quack, but I wrote an online order-processing system for an Internet pill-pusher, so had to know this stuff to design the medical questionnaire).

    Reminds me of the old joke: two geriatrics in a retirement home, both widowed, take a shine to each other and decide to engage in a bit of rumpy pumpy. Just as they’re about to get down to business, the old lady says, “just so you know, I have acute angina.” The old bloke says, “I hope so, ‘cos your tits are rubbish.”

  5. I propose the use of vitamins C, E, and Taxifolin (taxivital) which work together in the fight against cholesterol. They protect blood vessels before the creation of atherosclerotic plaques.

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