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This is interesting

Trans people taking hormone drugs ‘seven times more likely to have a stroke’
Those taking hormonal treatments while transitioning also more likely to suffer heart and lung problems, says study

Blood clots etc.

Menopausal women who take HRT also face higher risks – as do those on the pill often enough.


The bit that interests me is is this equal? Does testosterone have the same effect as estrogen? Or rather, does testosterone on a female gene set have the same effect as estrogen on a male gene set? Or even, does estrogen on a male gene set lead to the same risks as that extra HRT on a female gene set? The report says both have been looked at but doesn’t mention a difference.

It’s the difference that would be interesting. That dosing on hormones has its problems shouldn’t be a surprise, dosing on anything has its problems. But are these problems equal?

9 thoughts on “This is interesting”

  1. There’s a 3.5% chance of having a stroke or heart attack after having a tooth extraction. How does that compare?

    (Not having an infected tooth removed triples the chance of a stroke, but I haven’t been able to find the background figure that is tripled.)

  2. The article, as I read it in the Daily Mail, says ‘especially in women’. It goes on to say that women who took the oral treatment were at a 58 percent increased risk of developing potentially deadly blood clotting.

    Must admit I was most entertained by some detransitioned woman suing the eight healthcare workers who helped her transition into a man.

  3. Hormone therapy in general seems to be very bad for the human body. Acne, high blood pressure and insomnia are common symptoms among girls injecting T.

    They usually look like Dobby the House Elf after a couple of years.

  4. From what I’ve read T has much quicker effects than E. No idea if the side effects are higher risk, but from the speed difference that would be the way to bet.

  5. Bloke in the Fourth Reich

    As always there appears to be no link and as it’s become de rigeur to go to the papers with these things before they are published in something approximating an academic journal, I can’t be bothered to look for the paper that might not even be out yet.

    But, no, it’s an estrogen thing, not especially a testosterone one.

    Also, 1675 presumably young-skewed group observed over probably very short time is surely not going to provide enough person-years to see much different in major cardiovascular events.

  6. There’s a 3.5% chance of having a stroke or heart attack after having a tooth extraction. How does that compare?

    Rilly? 1 in 30 extractions are followed by stroke or heart attack?? Surely we would have noticed? Or does it mean a 3.5% increased risk?

    (Apologies if I’ve missed an invisible /sarc tag)

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